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User:Jukeboksi/Wiki.study/Natural therapeutics: Difference between revisions
User:Jukeboksi/Wiki.study/Natural therapeutics (edit)
Revision as of 08:06, 5 August 2022
, 5 August 2022→Autoimmune diseases: + == Rheumatoid arthritis and Osteoarthritis == + 'Characterisation of the cannabinoid receptor system in synovial tissue and fluid in patients with osteoarthritis and rheumatoid arthritis' at ncbi.nlm.nih.gov, a 2008 study published in w:Arthritis Research & Therapy + (yes, I know plain vanilla MediaWiki is not very good for storing information about information that affects more than one thing, will look into mw:Extension:Cargo)
(→Autoimmune diseases: + 'Medical Cannabis: What Research is Revealing' 1 hr video at arthritis.ca slides presented by Dr. Jason McDougall, Professor, Nova Scotia and moderated by Dr. Siân Bevan, Chief Science Officer of the Arthritis Society on 2021-09-15. Dr. McDougall's work was kindly funded by the Arthritis Society of Canada.) |
(→Autoimmune diseases: + == Rheumatoid arthritis and Osteoarthritis == + 'Characterisation of the cannabinoid receptor system in synovial tissue and fluid in patients with osteoarthritis and rheumatoid arthritis' at ncbi.nlm.nih.gov, a 2008 study published in w:Arthritis Research & Therapy + (yes, I know plain vanilla MediaWiki is not very good for storing information about information that affects more than one thing, will look into mw:Extension:Cargo)) |
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* https://herb.co/news/health/autoimmune-diseases/ | * https://herb.co/news/health/autoimmune-diseases/ | ||
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== Rheumatoid arthritis and Osteoarthritis == | |||
* [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2453762/ ''''''Characterisation of the cannabinoid receptor system in synovial tissue and fluid in patients with osteoarthritis and rheumatoid arthritis'''''' at ncbi.nlm.nih.gov], a 2008 study published in [[w:Arthritis Research & Therapy]] - Results: ''CB1 and CB2 protein and RNA were present in the synovia of OA and RA patients. Cannabinoid receptor stimulation of fibroblast-like cells from OA and RA patients produced a time-dependent phosphorylation of extracellular signal-regulated kinase (ERK)-1 and ERK-2 which was significantly blocked by the CB1 antagonist SR141716A. The endocannabinoids anandamide (AEA) and 2-arachidonyl glycerol (2-AG) were identified in the synovial fluid of OA and RA patients. However, neither AEA nor 2-AG was detected in synovial fluid from normal volunteers. FAAH was active in the synovia of OA and RA patients and was sensitive to inhibition by URB597 (3'-(aminocarbonyl) [1,1'-biphenyl]-3-yl)-cyclohexylcarbamate).'' | |||
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