User:Jukeboksi/Wiki.study/Natural therapeutics: Difference between revisions
imported>Jukeboksi (→Phytocannabinoids: THC was discovered in 1964, 24 years after CBD) |
imported>Jukeboksi (linking to "National Cancer Institute of USA on cancers and cannabis (health professional version)" and "National Cancer Institute of USA on cancers and cannabis (patient version)" + reorg) |
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Phytocannabinoids are '''harmless''' to '''healthy''' cannabinoid receptor containing '''cells'''. | Phytocannabinoids are '''harmless''' to '''healthy''' cannabinoid receptor containing '''cells'''. | ||
'''Links about cannabis and cancer''' | '''Links about cannabis and cancer''' | ||
* [https://www.cancer.gov/about-cancer/treatment/cam/hp/cannabis-pdq National Cancer Institute of USA on cancers and cannabis (health professional version)] | |||
* [https://www.cancer.gov/about-cancer/treatment/cam/patient/cannabis-pdq National Cancer Institute of USA on cancers and cannabis (patient version)] | |||
* http://www.calgarycmmc.com/c.htm index into studies about the health benefits of cannabis, letter 'c' lists cancers for which studies have been done. | * http://www.calgarycmmc.com/c.htm index into studies about the health benefits of cannabis, letter 'c' lists cancers for which studies have been done. | ||
* https://www.exposingtruth.com/123-cannabis-cancer/ | * https://www.exposingtruth.com/123-cannabis-cancer/ | ||
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* [https://www.youtube.com/watch?v=ccYeiuzFnYs Dr. Cristina Sanchez at Cannafest Prague 2015] | * [https://www.youtube.com/watch?v=ccYeiuzFnYs Dr. Cristina Sanchez at Cannafest Prague 2015] | ||
* [https://www.youtube.com/watch?v=W53Z33Vk5T8 Dr. Cristina Sanchez lecture in Australia] (no slideshow shots, sorry) | * [https://www.youtube.com/watch?v=W53Z33Vk5T8 Dr. Cristina Sanchez lecture in Australia] (no slideshow shots, sorry) | ||
'''Studies about cannabis and cancer''' | |||
* [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791144/ Anticancer mechanisms of cannabinoids] | |||
'''Testimonies about cannabis and cancer''' | |||
* http://drsircus.com/medical-marijuana/cannabis-cures-cancer/ | |||
'''See also: [[#Cancers and turmeric|Cancers and turmeric]]''' (intra-article link) | '''See also: [[#Cancers and turmeric|Cancers and turmeric]]''' (intra-article link) | ||
Revision as of 13:26, 23 July 2018
Nature provides us with many healing agents but these are often pushed to the periphery of public knowledge to ensure big pharma profits.
Blackberries
Blackberries kill antibiotic resistant staphylococcus aureus bacteria. Irish teen awarded prize for discovery.[1]
Cannabis
Cannabis is the oldest and most versatile medicine known to humankind.
Cannabis sativa and Cannabis indica are the main cannabis variants though most strains are mixes of these. A third cannabis line is the Cannabis ruderalis, a rugged northern cannabis that has adapted to flower even under northern long summer days.
The endocannabinoid receptors
Main article in wikipedia Endocannabinoid system
Human body contains 2 types of endocannabinoid receptors CB1 and CB2.
CB1 receptors
CB1 receptors predominantly located in the nervous system, connective tissues, gonads, glands, and organs[2].
CB2 receptors
CB2 receptors, primarily found in the immune system and also present in the spleen, liver, heart, kidneys, bones, blood vessels, lymph cells, endocrine glands, and reproductive organs[2].
Endocannabinoids
Endocannabinoids are produced by our own bodies from Arachidonic acid or Omega-6 fatty acid[3].
The two main endocannabinoids are Anandamide and 2-AG.
Anandamide
Anandamide was discovered in 1992 and it binds to both CB1 and CB2 receptors. The name comes from the Sanskrit word 'Ananda' meaning 'bliss' and amide from its chemistry.
It has been referred to as the endocannabinoid version of THC.
2-AG
2-Arachidonoylglycerol aka. 2-AG was discovered in 1994-1995.
Links about 2-AG
N-Arachidonoyl dopamine
N-Arachidonoyl dopamine discovered in 2000.
2-Arachidonyl glyceryl ether
2-Arachidonyl glyceryl ether discovered in 2001.
Virodhamine
Virodhamine discovered in 2002
Lysophosphatidylinositol
Lysophosphatidylinositol is a contender to be the 6th endocannabinoid.
Further reading
- https://hempedification.wordpress.com/2017/08/05/endocannabinoids-beyond-the-brain/
- http://profofpot.com/endocannabinoid-receptors/
Phytocannabinoids
Many people may know the 2 most prevalent phytocannabinoids, THC and CBD.
List of known phytocannabinoids from Wikipedia:
- THC (Tetrahydrocannabinol)
- THCA (Tetrahydrocannbinolic acid)
- CBD (Cannabidiol)
- CBDA (Cannabidiolic Acid)
- CBN (Cannabinol)
- CBG (Cannabigerol)
- CBC (Cannabichromene)
- CBL (Cannabicyclol)
- CBV (Cannabivarin)
- THCV (Tetrahydrocannabivarin)
- CBDV (Cannabidivarin)
- CBCV (Cannabichromevarin)
- CBGV (Cannabigerovarin)
- CBGM (Cannabigerol Monomethyl Ether)
- CBE (Cannabielsoin)
- CBT (Cannabicitran)
THC
Tetrahydrocannabinol was found in 1964[4] and it is the main psychoactive compound that brings the 'high' most recreational users are chasing.
THCA
Tetrahydrocannabinolic acid THCA is the what cannabis plants produce to fend off insects from harming it. In pure form THCA is a clear translucent crystalline of white color.
THC is produced from the raw THCA by a process called decarboxylation. Basically means to heat the stuff over certain temperature.
THCA found in raw marijuana apparently has some health enhancing properties. The issue is being researched.
CBD
Cannabidiol and it was isolated and identified from Cannabis sativa in 1940[4]. CBD is not psychoactive and it has the most medical applications of all phytocannabinoids.
“Cannabidiol has little affinity for CB1 and CB2 receptors but acts as an indirect antagonist of cannabinoid agonists.[5]”
- Hightimes in detail piece on CBD
- Leafly lists strains high in CBD
- Piece on CBD as anti-pain agent (contains ads)
- WHO preliminary report on CBD
CBDA
Cannabidiolic Acid is the raw form. Decarboxylating CBDA yields CBD.
CBN
CBG
“Cannabigerol has been shown to promote apoptosis in cancer cells and inhibit tumor growth in mice. It acts as an α2-adrenergic receptor agonist, 5-HT1A receptor antagonist, and CB1 receptor antagonist.[6] It also binds to the CB2 receptor.[6]”
CBC
CBL
CBV
THCV
Tetrahydrocannabivarin can be used to inhibit appetite.
Links about THCV
CBDV
CBCV
Cannabichromevarin
CBGV
Cannabigerovarin
CBGM
Cannabigerol Monomethyl Ether
CBE
Cannabielsoin
CBT
Cannabicitran
Cannabis therapeutics
Cannabis can be applied to treat a wide assortment of illnesses. In this case it is called medical cannabis.
Due to the inbuilt default to always take the safe route and also to backup the back of your fellow MD colleague the Wikipedia does not yield the right infos on how useful and versatile a medication cannabis is.
Research has been held back by arcane laws even as cannabis is the oldest medicine known to man and it should be gladly appreciated and not outlawed because of big pharma interests.
Alzheimer's disease and cannabis
Cannabis has been found to be beneficial for Alzheimer's sufferers. Especially true this is for THC which inhibits the formulation of toxic beta amyloid protein plaque on braincells which causes Alzheimer's disease.
- Wikipedia article on Alzheimer's disease research has only a few words about cannabis therapeutics and those are very sceptical.
Amyotrophic lateral sclerosis and cannabis
Cannabis helps with Amyotrophic lateral sclerosis (ALS) also known as Lou Gehrig's disease and motor neurone disease (MND).
Asthma and cannabis
Autism and cannabis
Autoimmune diseases and cannabis
Cannabis helps with many autoimmune diseases due to its anti-inflammatory and other properties.
Links about autoimmune diseases and cannabis
Rheumatoid arthritis and cannabis
Cannabis helps with Rheumatoid arthritis.
Links about Rheumatoid arthritis and cannabis
Lupus and cannabis
Cannabis helps with Systemic lupus erythematosus
Coeliac disease and cannabis
Cannabis helps with Coeliac disease.
Psoriasis and cannabis
Cannabis helps with Psoriasis when applied externally.
Type 1 diabetes and cannabis
Multiple sclerosis (MS) and cannabis
Cannabis is very good against Multiple sclerosis.
- http://herb.co/2016/07/28/marijuana-and-ms/
- https://www.learngreenflower.com/articles/440/treating-multiple-sclerosis-with-cannabis
Cancers and cannabis
Internet is rife with stories about winning the battle against cancer with the help of phytocannabinoids. What does the science say?
- Anti-proliferative - cannabis is against tumor growth [7]
- Anti-metastatic - cannabis is against cancer spreading to other parts in the body because of metastatic activity[7]
- Anti-angiogenetic - cannabis is against new blood vein growth to tumor[7]
- Apoptotic - cannabis causes cancer cells to programmedly kill themselves via Apoptosis. [7]
- Pain relief - cannabis works very well against the somatic and nonsomatic pains brought on by cancer.
- Appetite stimulator - cannabis helps maintain a good appetite.
- Anti-nauseatic - cannabis helps with the chemotherapy-induced nausea and vomiting. [8] if you receive chemotherapy.
Phytocannabinoids are harmless to healthy cannabinoid receptor containing cells.
Links about cannabis and cancer
- National Cancer Institute of USA on cancers and cannabis (health professional version)
- National Cancer Institute of USA on cancers and cannabis (patient version)
- http://www.calgarycmmc.com/c.htm index into studies about the health benefits of cannabis, letter 'c' lists cancers for which studies have been done.
- https://www.exposingtruth.com/123-cannabis-cancer/
Videos on the Internet about phytocannabinoid treatment of cancers
Cristina Sánchez is one of the foremost researchers into the anti-cancer qualities of cannabinoids of our time.
- Dr. Cristina Sanchez interview where she expains how apoptosis makes cancer cells kill themselves (a molecular biology research scientist who did her doctorates on exocannabinoids and cancers)
- Dr. Cristina Sanchez on how cannabinoids work against cancers
- Dr. Cristina Sanchez at Cannafest Prague 2015
- Dr. Cristina Sanchez lecture in Australia (no slideshow shots, sorry)
Studies about cannabis and cancer
Testimonies about cannabis and cancer
See also: Cancers and turmeric (intra-article link)
Leukemia and cannabis
There are 2 main types of Leukemia:
- Myeloid leukemia (of the bone marrow)
- Lymphoid leukemia (of the lymphatic node)
Links about Lympoid and Myeloid leukemia and cannabis
Links about Lymphoid leukemia and cannabis
- https://ocgreenrelief.org/medical-marijuana/cannabis-oil-acute-leukemia-2
- http://truemedmd.com/2014/06/cannabis-oil-acute-leukemia/
Links about Myeloid leukemia and cannabis
- http://www.leafscience.com/2013/10/14/cannabinoids-destroy-leukemia-cells-new-study-finds/
- http://www.healthmj.com/cancer/donavon-vizina-on-treating-acute-myeloid-leukemia-with-cannabis-oil/
Prostate cancer and cannabis
Cannabis helps with prostate cancer.
- herb.co/2017/01/13/prostate-cancer-cannabis/
Brain cancer and cannabis
Crohn's disease and cannabis
Study shows THC helps with Crohn's disease.
- https://theheartysoul.com/cannabis-crohns-disease-treatment-remission/
- http://ushealthtimes.com/cannabis-is-curing-stomach-and-bowel-diseases-considered-incurable-by-modern-medicine-us-health-times/
Epilepsy and cannabis
Cannabis can be used to treat epilepsy.
Migraines and cannabis
It has been suggested that clinical endocannabinoid deficiency syndrome (CEDS) may be causing migraines. Many studies found medical cannabis as an effective prophylaxis against migraine attacks, especially the high CBD strains.
- CBD Testers article on treating migraines with medical cannabis and link to the study 'Effects of Medical Marijuana on Migraine Headache Frequency in an Adult Population' at PubMed that the article is talking about.
- Abstracts of studies on migraines and medical cannabis at migrainebuds.com
Pain treatment with cannabis
“You just don't feel like thinking about the pain.”
“There is more to it than that.”
Cannabis is anti-inflammatory which helps relieve some of the pain. Pain is a signal of inflammation so counter-acting inflammation causing things cannabis naturally helps lower the pain.
Parkinsons disease and cannabis
Non-somatic issues with cannabis
Cannabis can help with various non-somatic problems such as psychiatry, depression and PTSD.
PTSD and cannabis
External links about cannabis as medicine
- http://www.calgarycmmc.com/ a large compendium on medical cannabis sorted alphabetically by ailment.
- http://www.cannabisconnections.tk/2018/03/700-medicinal-uses-of-cannabis-sorted.html
- http://www.encod.org/info/700-MEDICINAL-USES-OF-CANNABIS.html
- http://expand-your-consciousness.com/100-scientific-studies-agree-cannabis-annihilates-cancer/ about 100 nig.gov studies linked some cases briefly described.
- 71 medical uses of cannabis compiled by LearnGreenFlower.com
Literature about cannabis as a medicine
- MARIJUANA AS MEDICINE? The Science Beyond the Controversy, a book published in 2000 that you can read on-line from The National Academies Press .
Pineapple
Pineapple fruit and it's stem contain Bromelain, an enzyme with anti-cough properties.
In vitro and in vivo studies demonstrate that bromelain exhibits various fibrinolytic, antiedematous, antithrombotic, and anti-inflammatory activities.[9] Bromelain accounts for many therapeutic benefits like the treatment of angina pectoris, bronchitis, sinusitis, surgical trauma, and thrombophlebitis, debridement of wounds, and enhanced absorption of drugs, particularly antibiotics.[9]
Stevia
Stevia works against the Lyme disease.[10]
Turmeric
Turmeric contains curcumin, a curcuminoid.
Cancers and turmeric
Curcumin has been found to have anti-cancer properties. Curcumin interferes with cancer via multiple cell signaling pathways, including cell cycle, apoptosis, proliferation, survival, invasion, angiogenesis, metastasis and inflammation[11].
- Study: Curcumin and Cancer Cells: How Many Ways Can Curry Kill Tumor Cells Selectively?
- General info: Turmeric and cancers article by Cancer Research UK
- Case: Turmeric treatment heals woman suffering from blood cancer at TheOrganicDream.com
See also: Cancers and cannabis (intra-article link)
Alzheimer's and turmeric
- Optimized Turmeric Extract Reduces β-Amyloid and Phosphorylated Tau Protein Burden in Alzheimer’s Transgenic Mice suggests that turmeric may be useful for Alzheimer's sufferers as it has been shown to inhibit beta amyloid aggregation and secretation in mice.
See also: Alzheimer's and cannabis (intra-article link)
Information sources on natural therapeutics
References
- ↑ http://theorganicdream.com/2018/02/irish-teen-awarded-prestigious-prize-discovery-natural-substance-kills-antibiotic-resistant-bacteria/
- ↑ 2.0 2.1 https://patients4medicalmarijuana.wordpress.com/2017/07/06/how-and-why-your-brain-makes-its-own-cannabinoids/
- ↑ https://wakeup-world.com/2014/09/08/the-endocannabinoid-system-and-how-thc-cures-cancer/
- ↑ 4.0 4.1 https://en.wikipedia.org/wiki/Tetrahydrocannabinol
- ↑ Mechoulam, Raphael; Peters, Maximilian; Murillo-Rodriguez, Eric; Hanuš, Lumír O. (2007). "Cannabidiol – Recent Advances". Chemistry & Biodiversity. 4 (8): 1678–92. doi:10.1002/cbdv.200790147. PMID 17712814.
- ↑ 6.0 6.1 Cascio, MG; Gauson, LA; Stevenson, LA; Ross, RA; Pertwee, RG (2010). "Evidence that the plant cannabinoid cannabigerol is a highly potent α2-adrenoceptor agonist and moderately potent 5HT1A receptor antagonist". British Journal of Pharmacology. 159 (1): 129–41. doi:10.1111/j.1476-5381.2009.00515.x. PMC 2823359. PMID 20002104.
- ↑ 7.0 7.1 7.2 7.3 http://herb.co/2016/08/25/cannabis-kills-cancer/
- ↑ http://herb.co/2017/01/03/cannabis-chemotherapy-induced-nausea/
- ↑ 9.0 9.1 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3529416/
- ↑ https://www.healthspiritbody.com/lyme-disease-treatment/
- ↑ https://www.sciencedirect.com/science/article/pii/S0304383508002310